Dr. Imran Kazmi

  • M. Pharm, Ph.D
    Assistant Professor (Pharmacognosy and Phytochemistry)
    Office: Pharmacognosy Lab 1
    Phone: +91-9690717533
    Email: imran@theglocaluniversity.in

     RESEARCH 

    Broad area of Research includes Isolation, Characterization & Pharmacological Evaluation of phytoconstituents of pharmaceutical importance and drug developments.

    EDUCATION

    Qualification

    Year

    University

    B. Pharm 

    2008

     Jamia Hamdard University, New Delhi, India

    M. Pharm

    2010

    Jamia Hamdard University, New Delhi, India 

    Ph. D  

    2014

    Pacific University, Udaipur, India  

    Experiences:

    • Working as an Assistant Professor of Pharmacognosy and Phytochemistry for last 2 years in Glocal School of Pharmacy, The Glocal University, Saharanpur.

    • Expert in designing course curriculums of Pharmacy both undergraduate and post graduate Programmes.

    • Adroit in handling PCI, AICTE and UGC related works of academics.

    • Worked as an Assistant Professor of Pharmacognosy and Phytochemistry and dealt with the subjects like Pharmacognosy, Chemistry of natural products for 9 months in Doon College of Education Saharanpur.

    • Co-supervisor of M. Pharm students in Uttarakhand Technical University, Dehradun, Uttarakhand, India.

    • Faculty Development Programme of fourteen days Organized by KIET College, sponsored by DST Govt. of India.

    • Reviewer of Journals Expert opinion on Current Drug Delivery, Pharmaceutical Biology, Informa Health Care, International journal of pharmacy and pharmacology & Wudpecker journal of medical sciences, Phytotherapy research, Wiley Blackwell, International Journal of Medicine and Medical Sciences, Food function Fitoterapia, Journal of Pharmacy & Pharmacology, Life Sciences, Journal of Natural Medicine and Journal of Pharmacy and Bioallied Sciences. etc.

    • Evaluator and Question Paper Expert at UG level (Pharmacy) for Different Universities (SHIATS, Allahabad and UKTU, Dehradun and Glocal University, Saharanpur)

    • Worked as volunteer in the National Service Scheme (NSS) from 2007 - 2009.

    Skills And Expertise:

    • Expert in handling of Column Chromatography, HPTLC, HPLC, analytical instruments and techniques like UV, Biochemistry semi-auto analyzer, fully automated Heamatoanalyzer, cooling centrifuge.

    • Expert in microscopic technique.

    • Pharmacological evaluation ofAnti-diabetic, Anti-obesity, Anticonvulsant, Anxiolytic, Wound Healing, Anti-inflammatory, Anti-ulcer, Aphrodiastic, Anti-hyperlipidemic, Anticancerdrugs.

    • Expertise in Animal handling (Rat, Mouse, Rabbit, Guinea pig) - PO, IP, IM, SC and IV dosing, Blood collection from retro orbital plexus, tail vein, intracardiac and rabbit marginal ear vein.

    • Adroit in various animal models like Asthma, Diabetes, Anti-convulsant, Analgesics and anti-inflammatory, Hypertension, Ulcer, Uroliathiasis, Inflammatory bowel disease, Renal ischemia reperfusion, Cardiovascular disease and cancers.

    • Appreciable understanding of the concepts related to Intellectual Property Management and Regulatory Affairs & applications of Biostatistics in health sciences.

     

    ACHIEVEMENTS:

    • Qualified GATE (Graduate Aptitude Test in Engineering) with 94.90 percentile conducted by ISC Bangalore in 2008.

    • Reviewer of various scientific journals of international repute.

    • Awarded with AICTE scholarship during M. Pharm session (2008-2010).

    Research outcomes:

    Impact factor of research publications is 84 with an average impact of 2/publication

    SELECTED PUBLICATIONS

    S.No

    Title

    Type

    Journal

    Impact factor

    1

    Anti-diabetic potential of ursolic acid stearoyl glucoside: A new triterpenic gycosidic ester from Lantana camara

    Research

    Fitoterapia, Elsevier, 2012; 83: 853–858

    2.2

    2

    Fixed dose combination therapy Loperamide and Niacin ameliorates diethylnitrosamine- induced liver carcinogenesis in albino Wistar rats

    Research

    RSC Advances, Royal Society of Chemistry, 2015; 5: 679-696

    3.8

    3

    Cancer initiating properties of erythrosine supplemented withsub necrotic dose of diethyl nitrosamine: potential effects onbiochemical parameters of liver, Vitamin C and E

    Research

    Molecular & Cellular Toxicology, 2015, 11:0-0

    1.2

    4

    Anticancer effect of rosiglitazone in rats treated with N-nitrosodiethylamine via inhibition of DNA synthesis: an implication for hepatocellular carcinoma

    Research

    RSC Advances, Royal Society of Chemistry,2015: 5; 68385-68391

    3.8

    5

    Rutin Attenuate CarfilzomibInduced Cardiotoxicity Through Inhibition of NFκB, Hypertrophic Gene Expression and Oxidative Stress

    Research

    Cardiovascular Toxicology 2015 Dec 26.

    1.7

    6

    Therapeutic exploration of betulinic acid in chemically induced hypothyroidism

    Research

    Molelular & Cellular Biochemistry, 2014; 386(1-2): 27-34

    2.3

    7

    Combination of sulfamethoxazole and selenium in anticancer therapy: a novel approach.

    Research

    Molelular & Cellular Biochemistry, 2013; 384(1-2): 279-285

    2.3

    8

    Anticonvulsant activity of ethanol extracts of Vetiveria zizanioides roots in experimental mice

    Research

    Pharmaceutical Biology, 2013 Dec;51(12):1521-4

    1.2

    9

    Hepatoprotective potential of new steroid against carbon tetrachloride-induced hepatic injury

    Research

    Molelular & Cellular Biochemistry, 2013; 378(1-2): 275-81

    2.3

    10

    Antineoplastic potential of Bryophyllum pinnatum lam. on chemically induced hepatocarcinogenesis in rats

    Research

    Pharmacognosy Research, 2013; 5(4): 247-53.

    1.3

    11

    Talc used in anticancer drugs is promoter for diabetes in hepatocellular carcinoma induced rats

    Research

    European Journal of Cancer, 2014; 50: 247-248

    5.2

    12

    Pharmacological evaluation of anxiolytic activity of ursolic acid stearoyl glucoside isolated from Lantana camara

    Research

    CNS Neuroscience & Therapeutics, Wiley, 2012; 18(8): 707-708.

    4.5

    13

    Antiepileptic potential of ursolic acid stearoyl glucoside by GABA receptor stimulation

    Research

    CNS Neuroscience & Therapeutics, Wiley, 2012; 18(9): 799-800.

    4.5

    14

    Antiobesity potential of ursolic acid stearoyl glucoside by inhibiting pancreatic lipase

     

    Research

    European Journal of Pharmacology, Elsevier, 2013 709: 28-36

    2.7

    15

    Pharmacological Evaluation of Gatifloxacin in Chemically Induced Hepatocarcinogenesis: A New Tool for Hepatocellularcarcinoma Treatment

    Research

    Journal of Cancer Sciences & Research, OMICS, 2012; 5(1): 18-22

    5.2

    16

    Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats

    Research

    Journal of Ethnopharmacology, Elsevier, 2012; 141: 810– 816

    3.7

    17

    Anxiolytic otential of ursolic acid derivative—a stearoyl glucoside isolated from Lantana camara L. (Verbanaceae)

    Research

    Asian Journal of Tropical Medicine, Elsevier, 2013: 433-437

    1.1

    18

    Antifungal effect of new combination of gatifloxacin in combination with copper ions

    Research

    The Journal of Antibiotics, 2014; 67: 499-504

    2.7

    19

    Anticancer effect of of ursolic acid stearoyl glucoside against N-diethylnitrosamine induced hepatocellular carcinoma in rats

    Research

    Journal of Physiology & Biochemistry, Springer, 2013; 69: 687695

    2.6

    20

    Anti-inflammatory potential of a novel steroidal derivative from Bryophyllum pinnatum

    Research

    Fitoterapia, Elsevier, 2012; 83: 142–14

    2.2

    21

    Antiulcer and antioxidant activity of new steroid from Morus alba

    Research

    Life Sciences, 2013: 92; 202–210

    2.7

    22

    Polypharmacy (herbal and synthetic drug combination)-A novel approach in treatment of type-2 diabetes and its complications in rats

    Research

    Journal of Natural Medicine, Springer, 2013; 67; 662-671

    1.7

    23

    Preventive effect of metformin against N-nitrosodiethylamine-initiated hepatocellular carcinoma in rats

    Research

    Pharmaceutical Journal, Elsevier, 2012; 20: 365–370

    1.0

    24

    Evaluation of anxiolytic activity of embelin isolated from Embelia ribes

    Research

    Biomedicine & Aging Pathology, Elsevier, 2012; 2: 45-47

    --

    25

    Pharmacological, biochemical and toxicological evaluation of Potash Alum as anti-obesity agent

    Research

    International Journal of Pharmacy and Pharmaceutical Science, 2012; 4: 90-93

    0.38

    26

    Anti-obesity potential of potash alum: Pharmacological and Biochemical approach

     

    Research

    Pharmacologia, U.K., 2012; 3(12): 729-733

    --

    27

    Aphrodisiac properties of Polygonatum verticillatum leaf extract

    Research

    Asian Pacific Journal of Tropical Disease, Elsevier, 2012: S841-S845

    0.80

    28

    Pharmacological Role of Alstonia scholaris Leaves for its Anticonvulsant and SedativeAction

    Research

    American Journal of Phytomedicine and Clinical Therapeutics, 2013; 1: 478-490

    --

    29

    Comparison of protective and curative potential of Daucus carota root extract on renal ischemia reperfusion injury in rats.

    Research

    Pharmaceutical Biology, Informa Healthcare, 2013; 51: 856-862

    1.2

    30

    Anticonvulsant and depressant-like activity of ursolic acid stearoyl glucoside isolated from Lantana camara L. (verbanaceae)

    Research

    Asian Pacific Journal of Tropical Disease, Elsevier, 2012: S453-S456

    0.73

    31

    Formulation and evaluation of sustained release matrix tablet of rabeprazole using wet granulation technique

    Research

    Journal of Pharmacy & Bioallied Sciences 2014; 6(3): 180-184

    --

    32

    Six new glycosides from the leaves of Artocarpus heterophyllus Lam.

    Research

    International Journal of Pharmacy and Pharmaceutical Sciences, 2012; 4: 3

    --

    33

    Effect of Bryophyllum pinnatum Lam. on N-diethylnitrosamine induced hepatic injury in rats

    Research

    Pharmacologia, 2013; 4(2): 82-88

    --

    34

    Pharmacological and biochemical evaluation of potash alum as anti-obesity agent: A new tool for treatment of obesity

    Research

    Journal of Aging: Research and Clinical Practice, Germany Publisher, 2013: 32-34

    --

    35

    Antidiabetic potential of triterpenoid saponin isolated from Primula denticulate

    Research

    Pharmaceutical Biology, Informa Healthcare, 2014; 52: 750-755

    1.2

    36

    Anxiolytic effect of Oxalis corniculata (Oxalidaceae) in mice

    Research

    Asian Pacific Journal of Tropical Disease, Elsevier, 2012: S837-S840

    0.73

    37

    Advancement in multifunctional nanoparticles for the effective treatment of cancer

    Review

    Expert Opinion on Drug Delivery, Informa Health care, 2012; 9: 367-381

    4.9

    38

    Insight into the biomarkers as the novel anti-psoriatic drug discovery tool: A contemporary viewpoint

    Review

    Current Drug Discovery Technologies, BSP, 2012; 9: 48-62

    3.26

    39

    Biometals: New tools for treatment of obesity and its related metabolic disorders

    Review

    Journal of Aging: Research and Clinical Practice, Germany Publisher, 2012:11: 1-3

    --

     

    40

    Classical to current approach for the treatment of psoriasis

    Review

    Journal of Endocrine Metabolic Disorder, BSP, 2012; 12(3): 287-302

    2.80

    41

    Omega-3 fatty acids as pharmacotherapeutics in psoriasis: current status and scope of nanomedicine in its effective delivery

    Review

    Curr Drug Targets, 2013;14(6): 708-722

    3.26

    42

    Ectopic pregnancy: a review

    Review

    Archives of Gynecology & Obstet, 2013; 288:747–757

    1.4

    43

    Emergence of nanomedicine as cancer targeted magic bullets: recent development and need to address the toxicity apprehension

    Review

    Current Drug Discovery Technologies, Bentham Scien 2012; 9(4): 319-329

    --

    44

    Novel Approach for the Treatment of Cancer: Theranostic Nanomedicine.

    Review

    Pharmacologia, 3: 371-376

    --

    45

    Bryophyllum pinnatum: A review

    Review

    International Journal of Research in Biological Sciences 2012; 2(4): 143-149

    --


    Patent:

    • Patent on “Extraction and isolation of novel cardioprotective ursolic acid stearoyl glucoside from the leaves of Lantana camara Linn.” Official Journals of the Patent Office, Application No.273/DEL/2013 A, Isssue no. 34/2014, Page no. 32197.

    Books:

    • Reference book on “Characterization and Pharmacological evaluation of Lantana camara” (ISBN No: 978-3-8484-0483-4, Lambert publication, Germany).

    • Book on “Human, Physiology and Health Education” (ISBN No: 978-3-8484-4559-2, Lambert publication, Germany).

    • Book on “Neuropsychatric Disorders” (ISBN No: 978-3-659-13029-8,Lambert publication, Germany).

    • Reference book on “Ethnobotany, phytochemistry and pharmacology of Morus alba (Moraceae)” (ISBN No: 978-3-659-12802-8, Lambert publication, Germany).

    • Reference book on “Synthesis and antimicrobial activity of Phthalimide derivatives” (ISBN No: 978-3-8454-1838-4, Lambert publication, Germany).

    Conferences and Seminars Attended:

    • Participated in AICTE sponsored national seminar on “Emerging trends in Pharmaceutical sciences”.

    • Participated in regional seminar on “Intellectual property protection and management ” organized by Central council for research in unani medicine.

    • Participated in national seminar on “Current challenges and opportunities in indian pharmaceutical industry”

    • Participated in the seminar organized by Indian congress of pharmacy and pharmaceutical sciences, New delhi.

    • Oral presentation on “Wound healing activity of ursolic acid stearoyl glucoside isolated from Lantana camara”, in an international conference NHPBMS/ORAL/ROLL NO. / 43.

    • Oral presentation on “Combination therapy in diabetes (Synthetic and herbal medicine): A novel approach”, in an international conference NHPBMS/ORAL/ROLL NO. / 15.

    • "Pharmacological evaluation of anxiolytic property of Dolichandrone falcate leaves in experimental animal” organized by Shoolini University, Himachal Pradesh sponsored by DST, Govt. of India.

    • "Ajuga bracteosa: A plant with potential anti-ulcerogenic activity” organized by Shoolini University, Himachal Pradesh sponsored by DST, Govt. of India.

    Societies:

    • Life member of Indian Post-Graduate Association (IPGA).

    Guidance to PG Students:

    • As a Co-Guide five students on “Pharmacological evaluation of Rosiglitazone as an anticancer agent in chemically induced hepatocarcinogenesis”, “Role of antidiabetic agent Metformin as an anticancer agent in chemically induced hepatocarcinogenesis”, “Anticancer activity of ursolic acid stearoyl glucoside from Lantana camara”, Antiulcer activity of ursolic acid stearoyl glucoside from Lantana camara” and Antimicrobial activity of ursolic acid stearoyl glucoside from Lantana camara” from Uttarakhand Technical University.